Monday February 19th 2018

Revised diagnostic criteria of multiple sclerosis.

Authors: Milo R, Miller A Abstract Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system (CNS) of presumed autoimmune etiology, characterized by localized areas of inflammation, demyelination, axonal loss and gliosis in the brain and spinal cord. Although the clinical presentation and course of the disease are highly variable, several disease types can be recognized, including relapsing-remitting-(RR), primary-progressive-(PP), secondary-progressive-(SP), progressive-relapsing-(PR) MS and clinically-isolated syndrome (CIS). There is no single clinical feature or diagnostic test that is sufficient to diagnose MS, and the diagnosis is mainly a clinical one. Over the years, several sets of criteria have been proposed for the diagnosis of MS, based on…

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Revised diagnostic criteria of multiple sclerosis.

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