Wednesday August 23rd 2017

Targeting the Sphingosine-1-phosphate Signaling with FTY720 in Obesity Related Breast Cancer Progression

In this study, we found that obesity in animal breast cancer models increases SphK1 and levels of S1P in both tumor and its microenvironment. To examine the contribution of increased S1P to breast cancer progression and metastasis, mice were treated with FTY720 to disrupt the S1P signaling, which is strengthened by obesity. (Source: Journal of Surgical Research)

Visit site:

Targeting the Sphingosine-1-phosphate Signaling with FTY720 in Obesity Related Breast Cancer Progression

Leave a Comment

More from category

Novartis launches MS study using data collected from smartphones
Novartis launches MS study using data collected from smartphones

Novartis (NYSE:NVS) said today that it is launching a research study to better understand the daily challenges facing [Read More]

McDonald criteria: MS diagnosis guidelines
McDonald criteria: MS diagnosis guidelines

Learn about the McDonald criteria. What is dissemination in space, what is dissemination in time, and what additional [Read More]

Multiple sclerosis: Are we close to a cure?
Multiple sclerosis: Are we close to a cure?

Read this article: Multiple sclerosis: Are we close to a cure? [Read More]

Medical News Today: McDonald criteria: MS diagnosis guidelines
Medical News Today: McDonald criteria: MS diagnosis guidelines

Learn about the McDonald criteria. What is dissemination in space, what is dissemination in time, and what additional [Read More]

Medical News Today: Multiple sclerosis: Are we close to a cure?
Medical News Today: Multiple sclerosis: Are we close to a cure?

Discoveries and breakthroughs in multiple sclerosis research are building momentum, but just how close are we to [Read More]