Monday February 19th 2018

The Transcription Factor IRF8 Activates Integrin-Mediated TGF-β Signaling and Promotes Neuroinflammation

Yuko Yoshida, Ryusuke Yoshimi, Hiroaki Yoshii, Daniel Kim, Anup Dey, Huabao Xiong, Jeeva Munasinghe, Itaru Yazawa, Michael J. O’Donovan, Olga A. Maximova, Suveena Sharma, Jinfang Zhu, Hongsheng Wang, Herbert C. Morse, Keiko Ozato. Recent epidemiological studies have identified interferon regulatory factor 8 (IRF8) as a susceptibility factor for multiple sclerosis (MS). However, how IRF8 influences the neuroinflammatory dise…. (Source: Immunity)

Visit site:

The Transcription Factor IRF8 Activates Integrin-Mediated TGF-β Signaling and Promotes Neuroinflammation

Leave a Comment

More from category

What side effects can result from interferon?
What side effects can result from interferon?

Interferon is used to treat several health conditions, but it has a range of side effects. We look at how these vary in [Read More]

FDA Clears Higher-Dose Glatopa Generic for MS FDA Clears Higher-Dose Glatopa Generic for MS
FDA Clears Higher-Dose Glatopa Generic for MS FDA Clears Higher-Dose Glatopa Generic for MS

Glatopa 40 mg/mL joins already-approved Glatopa 20 mg/mL, a glatiramer acetate generic for treatment of relapsing forms [Read More]

DIY faecal transplants carry risks including HIV and hepatitis, warn experts
DIY faecal transplants carry risks including HIV and hepatitis, warn experts

Faecal transplants have been used in medical settings to tackle superbugs, but following YouTube videos at home is too [Read More]

High blood pressure drug may also help prevent onset of type 1 diabetes
High blood pressure drug may also help prevent onset of type 1 diabetes

A drug commonly used to control high blood pressure may also help prevent the onset of type 1 diabetes in up to 60 [Read More]

Eye and balance exercises may ease multiple sclerosis symptoms
Eye and balance exercises may ease multiple sclerosis symptoms

Reuters Health - People with multiple sclerosis who do balance and eye movement exercises may feel steadier on their [Read More]