Sunday August 20th 2017

The Transcription Factor IRF8 Activates Integrin-Mediated TGF-β Signaling and Promotes Neuroinflammation

Yuko Yoshida, Ryusuke Yoshimi, Hiroaki Yoshii, Daniel Kim, Anup Dey, Huabao Xiong, Jeeva Munasinghe, Itaru Yazawa, Michael J. O’Donovan, Olga A. Maximova, Suveena Sharma, Jinfang Zhu, Hongsheng Wang, Herbert C. Morse, Keiko Ozato. Recent epidemiological studies have identified interferon regulatory factor 8 (IRF8) as a susceptibility factor for multiple sclerosis (MS). However, how IRF8 influences the neuroinflammatory dise…. (Source: Immunity)

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The Transcription Factor IRF8 Activates Integrin-Mediated TGF-β Signaling and Promotes Neuroinflammation

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