Friday October 20th 2017

Management of psoriasis vulgaris and multiple sclerosis with fumaric acid

To the Editor: Psoriasis vulgaris has not only been associated with several comorbidities like metabolic syndrome and cardiovascular disease, but also with neurologic disorders like multiple sclerosis (MS). New-onset psoriatic lesions and exacerbations have been described after treatment with biologics for MS, mainly interferon-beta (INF-β) as well as with other biologics such as natalizumab. INF-β is the first-line treatment for clinically isolated syndrome with the high risk for MS development or for relapsing-remitting multiple sclerosis (RR-MS). Fumaric acids have been a well-established therapy for psoriasis vulgaris, mainly in Germany under the trade name Fumaderm–a mixture of dimethyl fumarate (DMF) and 3 salts of ethyl hydrogen fumarate, with DMF considered to be the active ing…

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Management of psoriasis vulgaris and multiple sclerosis with fumaric acid

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