Thursday January 18th 2018

Safety and efficacy of ofatumumab in relapsing-remitting multiple sclerosis: A phase 2 study

Conclusions: Ofatumumab (up to 700 mg) given 2 weeks apart was not associated with any unexpected safety concerns and was well tolerated in patients with RRMS. MRI data suggest a clinically meaningful effect of ofatumumab for all doses studied. Results warrant further exploration of ofatumumab in RRMS. Classification of evidence: This study provides Class II evidence that in patients with RRMS, ofatumumab compared with placebo does not increase the number of serious adverse events and decreases the number of new MRI lesions. (Source: Neurology)

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Safety and efficacy of ofatumumab in relapsing-remitting multiple sclerosis: A phase 2 study

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