Tuesday October 17th 2017

Vitamin D levels in Indian systemic lupus erythematosus patients: association with disease activity index and interferon alpha

IntroductionLow levels of vitamin D3 have been associated with several autoimmune disorders including multiple sclerosis, rheumatoid arthritis, type 1 diabetes and systemic lupus erythematosus (SLE). The major source of vitamin D3 is sunlight but exposure of SLE patients to UV rays has been shown to exacerbate disease pathology. Studies in various populations have shown an association between low vitamin D levels and higher SLE disease activity. Methods: We enrolled 129 patients who fulfilled American College of Rheumatology criteria in the study. There were 79 treatment naive cases and 50 patients who were under treatment for underlying SLE. There were 100 healthy subjects from similar geographical areas included as controls. Plasma 25-OH vitamin D3 and interferon (IFN)-alpha levels were …

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Vitamin D levels in Indian systemic lupus erythematosus patients: association with disease activity index and interferon alpha

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