Friday October 20th 2017

Narcolepsy with cataplexy and comorbid immunopathological diseases

This study reported on the comorbid immunopathological diseases associated with narcolepsy. One‐hundred and fifty six narcoleptic patients with a mean age at diagnosis of 39.1 ± 17.8 years (range, 6–70 years) were assessed using the clinical history, physical and neurological examinations, sleep questionnaires, neuroimaging and human leucocyte antigen typing. Diagnosis was confirmed by polysomnography followed by a multiple sleep latency test or by measuring hypocretin‐1 levels. Patients with immunopathological diseases were matched for gender and age at the onset of narcoleptic symptoms with narcoleptic patients without immunopathological diseases. Twenty‐six patients (16.6%; 50% women; one familial, 25 sporadic) had one or more immunopathological diseases associated: autoimm…

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Narcolepsy with cataplexy and comorbid immunopathological diseases

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