Sunday January 21st 2018

Statins may slow progression of MS

ConclusionThis was an early stage, phase II trial, which found that simvastatin reduced the rate of brain shrinkage in patients in the later stages of MS. The results are promising and warrant a larger phase III trial, examining whether the drug could slow the disease in patients at this stage of MS.  It should be noted that although simvastatin had some effect on outcomes in one disability scale and one symptom scale, the trial was primarily aimed at measuring the effect on brain shrinkage, rather than patients’ symptoms.To conclude, it is unclear what effect simvastatin, if any, would have on long-term quality of life for MS patients.A final interesting point is how simvastatin is actually reducing brain shrinkage. If we discovered the mechanisms involved, this could lead to new treat…

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Statins may slow progression of MS

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