Monday December 18th 2017

Blocking LINGO-1 Does Not Affect Inflammatory Markers in the Cerebrospinal Fluid of Individuals with Multiple Sclerosis (P1.186)

CONCLUSIONS: After treatment with BIIB033, a monoclonal antibody to LINGO-1, there were no significant changes in inflammatory markers in the CSF of study participants with RRMS and SPMS. This is similar to what has been observed in preclinical models of MS with LINGO-1 blockade.Study Supported by: Biogen IdecDisclosure: Dr. Ranger has received personal compensation for activities with Biogen Idec. Dr. Ranger holds stock and/or stock options in Biogen Idec which sponsored research in which Dr. Ranger was involved as an investigator. Dr. Ray has received personal compensation for activities with Biogen Idec. Dr. Ray holds stock and/or stock options in Biogen Idec which sponsored research in which Dr. Ray was involved as an investigator. Dr. Szak has received personal compensation for activi…

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Blocking LINGO-1 Does Not Affect Inflammatory Markers in the Cerebrospinal Fluid of Individuals with Multiple Sclerosis (P1.186)

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