Saturday December 16th 2017

Delayed Third Degree Atrioventricular Block With Pacemaker Placement In A Multiple Sclerosis Patient On Fingolimod Treatment (P2.211)

CONCLUSIONS:Recent case studies including ours point at late occurrence of life-threatening cardiac side effects in patients on fingolimod. We bring up three hypotheses for discussion: autonomic dysfunction related to the brainstem relapse, adverse event associated with fingolimod treatment, or most likely, a combination of both. Hence, surveillance for similar incidents should continue to identify additional risk factors for cardiac adverse events.Disclosure: Dr. Sellner has received personal compensation for activities with Biogen Idec, Terumo, Tatiopharm, and Merck Serono. Dr. Holl has received personal compensation for activities with Biogen Idec and Merck Serono for attending scientific meetings. Dr. Wipfler has received personal compensation for activities with Merck Serono, Bayer Ph…

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Delayed Third Degree Atrioventricular Block With Pacemaker Placement In A Multiple Sclerosis Patient On Fingolimod Treatment (P2.211)

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