Monday December 18th 2017

Effect of Ceralifimod (ONO-4641), a Sphingosine-1-Phosphate Receptor-1 and -5 Agonist, on Magnetic Resonance Imaging Outcomes in Patients with…

CONCLUSIONS: There were notable reductions in the numbers of new/enlarging T2 lesions in patients switching from placebo to active treatment in the extension study, while efficacy was sustained for patients on continuous active treatment.Study Support: Merck Serono SA, Geneva, Switzerland; EMD Serono, Inc., Rockland, MA, USA; Ono Pharmaceutical Co. Ltd, Osaka, JapanDisclosure: Dr. Bar-Or has received personal compensation for activities with Amplimmune, Aventis, Bayhill Therapeutics, Berlex/Bayer, Biogen Idec, BioMS, Diogenix, Eli Lilly & Company, EMD Serono, Genentech, Inc., Genzyme, GlaxoSmithKline, Inc., Guthy-Jackson/GGF, Medimmune, Mitsubishi Pharma, Novartis, Ono Pharma, Receptos, Roche, Sanofi-Aventis Pharmaceuticals, Inc., Teva Neuroscience, and Wyeth Pharmaceuticals. Dr. Bar-O…

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Effect of Ceralifimod (ONO-4641), a Sphingosine-1-Phosphate Receptor-1 and -5 Agonist, on Magnetic Resonance Imaging Outcomes in Patients with…

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