Monday December 18th 2017

Gestational Exposure to Natalizumab and Pregnancy Outcomes_Results From a Prospective Cohort with Relapsing Remitting Multiple Sclerosis (P4.156)

ConclusionThis is the largest prospective controlled study of natalizumab exposure in pregnancy, suggesting no increase in risk for major malformations. The benefits of natalizumab continuation must be weighed against high dose steroid treatment these women would need upon relapse following discontinuation. Natalizumab does not appear to increase the baseline risk for major malformations in exposed pregnancies. Further studies are needed for long term effects in these exposed childrenDisclosure: Dr. Ebrahimi has received personal compensation for activities with Novartis. Dr. Herbstritt has nothing to disclose. Dr. Gold has received personal compensation in an editorial capacity for Bayer Pharmaceuticals Corp., Biogen Idec, Merck Serono, Novartis, and Teva Neuroscience. Dr. Gold has receiv…

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Gestational Exposure to Natalizumab and Pregnancy Outcomes_Results From a Prospective Cohort with Relapsing Remitting Multiple Sclerosis (P4.156)

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