Monday December 18th 2017

Natalizumab Treatment Improves Walking Speed in MS Patients: A Post Hoc Analysis of AFFIRM (S4.006)

CONCLUSIONS: Patients with CIWS had better self-reported physical functioning. Natalizumab increased the probability of CIWS; treatment effects were larger and occurred earlier in patients with higher disability but were significant even in patients with lower disability. Most patients with CIWS did not meet criteria for EDSS improvement, suggesting CIWS may be more sensitive than EDSS in capturing improved ambulation in relapsing-remitting MS patients.Study Supported by: Biogen Idec Inc.Disclosure: Dr. Rudick has received personal compensation for activities with Novartis and Genzyme Corporation. Dr. Rudick has received license fee payments from a patent. Dr. Rudick has received research support from Genzyme Corporation and Novartis. Dr. Hutchinson has received personal compensation for a…

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Natalizumab Treatment Improves Walking Speed in MS Patients: A Post Hoc Analysis of AFFIRM (S4.006)

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