Thursday December 14th 2017

Preclinical Efficacy and Phase I Clinical Testing of ATX-MS1467, an Antigen-Specific Immunotherapy for Multiple Sclerosis (P1.189)

CONCLUSIONS: Treatment of MS patients with ATX-MS-1467 appears to be safe and well tolerated. There is preliminary evidence of disease improvement in patients with RMS, which is supported by efficacy data from pre-clinical models. These results favor further investigation of ATX-MS-1467 as a first-in-class, antigen-specific agent designed to improve standard of care in MS.Study supported by: Apitope Ltd, Bristol UK, and Merck Serono SA Geneva, Switzerland, a subsidiary of Merck KGaA, Darmstadt, Germany.Disclosure: Dr. Wraith has received personal compensation for activities with Apitope International NV as found and CSO. Dr. Wraith holds stock and/or stock options in Apitope International NV, which sponsored research in which Dr. Wraith was involved as an investigator. Dr. Wraith has recei…

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Preclinical Efficacy and Phase I Clinical Testing of ATX-MS1467, an Antigen-Specific Immunotherapy for Multiple Sclerosis (P1.189)

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