Monday January 22nd 2018

The Evaluation Of Environmental Factors In The Disease Penetrance Of Cervical Dystonia (P2.043)

We report the results of data collected from 67 matched sibling- pairs. Univariate logistic regression analysis showed a significant association between history of all car accidents p=0.008 (car accidents without hospitalisation p=0.046, OR 2.33, 95% CI 1.01-5.36; car accidents with hospitalisation p=0.006, 0R 5.3, 95% CI 1.59- 17.62), all surgical procedures (p=0.027, OR 5.8, 95% CI 1.22- 27.60), and ever having depression (p=0.025, OR 2.77, 95% CI 1.44- 6.77) and proband status. A multivariate model was fitted which showed that car accidents that required hospitalisation remained significantly associated with case status (p=0.013, OR 6.0, 95% CI 1.45- 28.86).ConclsuionCar accidents are often associated with soft tissue trauma, particularly minor neck trauma and likely act to increase ris…

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The Evaluation Of Environmental Factors In The Disease Penetrance Of Cervical Dystonia (P2.043)

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