Friday December 15th 2017

Transient Neurologic Worsening after Initiation of Dimethyl Fumarate Therapy in Progressive Multiple Sclerosis Patients (P2.228)

CONCLUSIONS: Patients with progressive forms of MS may experience a transient worsening of neurologic function following initiation of therapy with DMF. This effect appears independent of the subtype of progressive disease and not related to the well described adverse effects associated with DMF therapy. It is likely that this worsening is caused by a conduction block as it reverses with cessation of treatment. Study Supported by: None.Disclosure: Dr. Stark has received personal compensation for activities with Biogen Idec as a speaker. Dr. Chirls has nothing to disclose. Dr. Sadiq has nothing to disclose. (Source: Neurology)

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Transient Neurologic Worsening after Initiation of Dimethyl Fumarate Therapy in Progressive Multiple Sclerosis Patients (P2.228)

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