Wednesday February 21st 2018

Pregnancy outcomes in patients exposed to interferon beta-1b

Introduction Multiple sclerosis (MS) is a chronic autoimmune demyelinating disease of the central nervous system that is usually diagnosed in a patient’s 20s or 30s and is more common in women than in men.1 Given this typical patient profile, many patients with MS are women in their reproductive years. None of the currently approved disease-modifying therapies (DMTs) for patients with MS are recommended for use during pregnancy. Furthermore, all of these medications have been given a pregnancy category B, C, D or X by the US Food and Drug Administration, indicating that in the best case (category B), animal studies have failed to identify potential harmful effects of the medication but long-term safety data in humans are not available or, in the worst case (category X), studies in human pa…

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Pregnancy outcomes in patients exposed to interferon beta-1b

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