Sunday February 18th 2018

Elevated body temperature is linked to fatigue in an Italian sample of relapsing–remitting multiple sclerosis patients

Abstract Elevated body temperature was recently reported for the first time in patients with relapsing–remitting multiple sclerosis (RRMS) relative to healthy controls. In addition, warmer body temperature was associated with worse fatigue. These findings are highly novel, may indicate a novel pathophysiology for MS fatigue, and therefore warrant replication in a geographically separate sample. Here, we investigated body temperature and its association to fatigue in an Italian sample of 44 RRMS patients and 44 age- and sex-matched healthy controls. Consistent with our original report, we found elevated body temperature in the RRMS sample compared to healthy controls. Warmer body temperature was associated with worse fatigue, thereby supporting the notion of endogenous temperatur…

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Elevated body temperature is linked to fatigue in an Italian sample of relapsing–remitting multiple sclerosis patients

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