Saturday February 24th 2018

Polymerized Nano-curcumin attenuates neurological symptoms in EAE model of multiple sclerosis through down regulation of inflammatory and oxidative…

Authors: Mohajeri M, Sadeghizadeh M, Najafi F, Javan M Abstract Multiple Sclerosis (MS) is an inflammatory demyelinating disorder of central nervous system (CNS). Polyphenol curcumin has been used in traditional medicine as an effective drug for a variety of diseases. Different formulations of curcumin are introduced to increase its stability and effectiveness. Here we have examined the effect of polymerized form of Nano-Curcumin (PNC) on experimental autoimmune encephalomyelitis (EAE) as an animal model of MS. EAE was induced in female Lewis rats and PNC or curcumin was daily administrated intraperitonealy from day 12 to 29 post immunization. When the prophylactic effect of PNC was under investigation, rats received PNC from the first day of immunization. Treatment with PNC result…

Read this article: 

Polymerized Nano-curcumin attenuates neurological symptoms in EAE model of multiple sclerosis through down regulation of inflammatory and oxidative…

Leave a Comment

More from category

Multiple sclerosis: Skin cells may help to repair nerve damage
Multiple sclerosis: Skin cells may help to repair nerve damage

Researchers could be on the verge of a new treatment for multiple sclerosis; they reveal how transplanting neural stem [Read More]

Medical News Today: Multiple sclerosis: Skin cells may help to repair nerve damage
Medical News Today: Multiple sclerosis: Skin cells may help to repair nerve damage

Researchers could be on the verge of a new treatment for multiple sclerosis; they reveal how transplanting neural stem [Read More]

Researchers discover how the body skillfully extinguishes inflammation
Researchers discover how the body skillfully extinguishes inflammation

Inflammation needs energy An important source for this energy is oxygen, which is indispensable for the cells of the [Read More]

MS patients who feel stigmatized more likely to suffer from depression
MS patients who feel stigmatized more likely to suffer from depression

People with Multiple Sclerosis -- MS -- who feel stigmatized are more likely to suffer from depression, according to [Read More]

Stigma increases risk of depression for people with Multiple Sclerosis
Stigma increases risk of depression for people with Multiple Sclerosis

(Penn State) People with Multiple Sclerosis -- MS -- who feel stigmatized are more likely to suffer from depression, [Read More]