Monday February 19th 2018

Myeloid cell-based therapies in neurological disorders: how far have we come?

Publication date: Available online 8 October 2015 Source:Biochimica et Biophysica Acta (BBA) – Molecular Basis of Disease Author(s): Chotima Böttcher, Josef Priller The pathogenesis of neurological disorders such as multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS) and Alzheimer’s disease (AD) is multifactorial and incompletely understood. The development of therapies for these disorders of the central nervous system (CNS) is thus far very challenging. Neuroinflammation is one of the processes that contribute to the pathogenesis of CNS diseases, and therefore represents an important therapeutic target. Myeloid cells derived from the bone marrow are ideal candidates for cell therapy in the CNS as they are capable of targeting the brain and providing neuroprotective and ant…

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Myeloid cell-based therapies in neurological disorders: how far have we come?

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