Saturday February 24th 2018

Purinergic Receptors as Potential Therapeutic Targets in Alzheimer’s Disease.

Authors: Woods LT, Ajit D, Camden JM, Erb L, Weisman GA Abstract Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by a progressive loss of memory and cognitive ability and is a serious cause of mortality. Many of the pathological characteristics associated with AD are revealed post-mortem, including amyloid-β plaque deposition, neurofibrillary tangles containing hyperphosphorylated tau proteins and neuronal loss in the hippocampus and cortex. Although several genetic mutations and risk factors have been associated with the disease, the causes remain poorly understood. Study of disease-initiating mechanisms and AD progression in humans is inherently difficult as most available tissue specimens are from late-stages of disease. Therefore, AD researchers rely on …

From:  

Purinergic Receptors as Potential Therapeutic Targets in Alzheimer’s Disease.

Leave a Comment

More from category

Multiple sclerosis: Skin cells may help to repair nerve damage
Multiple sclerosis: Skin cells may help to repair nerve damage

Researchers could be on the verge of a new treatment for multiple sclerosis; they reveal how transplanting neural stem [Read More]

Medical News Today: Multiple sclerosis: Skin cells may help to repair nerve damage
Medical News Today: Multiple sclerosis: Skin cells may help to repair nerve damage

Researchers could be on the verge of a new treatment for multiple sclerosis; they reveal how transplanting neural stem [Read More]

Researchers discover how the body skillfully extinguishes inflammation
Researchers discover how the body skillfully extinguishes inflammation

Inflammation needs energy An important source for this energy is oxygen, which is indispensable for the cells of the [Read More]

MS patients who feel stigmatized more likely to suffer from depression
MS patients who feel stigmatized more likely to suffer from depression

People with Multiple Sclerosis -- MS -- who feel stigmatized are more likely to suffer from depression, according to [Read More]

Stigma increases risk of depression for people with Multiple Sclerosis
Stigma increases risk of depression for people with Multiple Sclerosis

(Penn State) People with Multiple Sclerosis -- MS -- who feel stigmatized are more likely to suffer from depression, [Read More]