Thursday January 18th 2018

Effects of estrogen treatment combat multiple sclerosis in mice

FINDINGSA study by UCLA researchers reveals the cellular basis for how the hormone estrogen protects against damage to the central nervous system in women with multiple sclerosis, or MS. The researchers found that estrogen treatment exerts positive effects on two types of cells during disease — immune cells in the brain as well as cells called oligodendrocytes.BACKGROUNDUCLADr. Rhonda VoskuhlMultiple sclerosis is a chronic autoimmune, neurodegenerative disease marked by visual impairment, weakness and sensory loss, as well as cognitive decline. These symptoms emerge when inflammatory immune cells destroy the myelin sheath that surrounds nerve cells, known as axons, and that acts as a form of protective insulation for those cells.The third trimester of pregnancy previously has been shown …

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Effects of estrogen treatment combat multiple sclerosis in mice

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